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Pathophysiology of Myocardial Ischemia and Reperfusion

The stone heart was the fear of the surgeon in the early days of open heart surgery. This form of ischemia and reperfusion injury plays also a role in modern interventional cardiology. This book gives insight in the knowledge gathered on this subject several years ago. This experience has been made available, because nowadays with the advent of gene expression and stem cell therapy this background has to be considered since many events occur in the venous circulation opening a complex cascade of events leading to completely different exits.

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Cover

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Table of contents

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1

Reperfusion injury

Guerci, A. D.

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2

The evolution of ischemic and reperfusion injury

Glogar, D. H.

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3

Purine Metabolism of the Heart

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4

Sustained Anaerobic Metabolism After Recanalization of Coronary Artery in Acute Myocardial Infarction

Nanto, S., Kodama, K., Naka, M., Taniura, K., Tamai, J., Koretsune, Y., Hori, M., and Inoue, M.

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5

Failure of Postischemic ATP Repletion by Adenosine to Improve Regional Myocardial Function

Hoffmeister, H. M., Mauser, M., and Schaper, W.

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6

Metabolic Changes of Glucose, Lactate and Free Fatty Acids During Ischemia and Subsequent Reperfusion

Korb, H., Hoeft, A., Hunneman, D. H., Wolpers, H. G., and Hellige, G.

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7

Oxygen-Debt and -Repayment in the Early Phase of Myocardial Ischemia

Korb, H., Hoeft, A., Wolpers, H. G., and Hellige, G.

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8

Comparative electrophysiological effects of coronary venous versus systemic intravenous procainamide on acutely ischemic myocardium

Meesmann, M., Karagueuzian, H. S., Ino, T., McCullen, A., Mandel, W. J., and Peter, T.

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9

Quantitative Assessment of Collateral Flow in Patients with Ischemic Heart Disease

Kupper, W., Hamm, C. W., and Bleifeld, W. H.

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10

Left Main Coronary Artery Stenosis: Evaluation by Coronary Sinus Blood Flow, Lactate Metabolism and Holter Monitoring

Hamm, C. W., Kupper, W., and Bleifrei, W.

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11

Myocardial Prodection, Complex Laboratory Examinations and their Computerized Evaluation

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12

Acute Myocardial Ischemic Reduction with Ibuprofen in the Isolated Perfused Rabbit Heart

Wetstein, L.

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13

Effect of Dipyridamole on Coronary Flow: A Thermodilution Study of the Coronary Reserve

Berland, J., Cribier, A., and Letac, B.

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14

Coronary Blood Flow Modifications After Administration of Captopril

Mattioli, G., Zenaro, R. G., Benassi, A., Modena, M, G., and Luppi, G.

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15

Cold Pressor Test, Incremantal Cardiac Pacing, Coronary Hemodynamics and Coronary Sinus Blood Rheology in Patients with Angina Pectoris and Normal Coronary Angiogram

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16

Comparison of the effects of coronary artery occlusion on regional myocardial blood flow distribution and necrosis in conscious primates and dogs

Lavallee, M., and Vatner, S. F.

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17

Metabolic consequences of myocardial ischemia and assessment of coronary sinus interventions

Schelbert, H. R., and Schwaiger, M.

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18

Panel Discussion Marker of Ischemia, Marker of Reperfusion Injury

Vatner, S. F., and Schelbert, H. R.

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19

Effects of ischemia on the canine myocardial -receptor-effector mechanism

Spiss, C. K., Weindlmayr-Goettel, M., Zimpfer, M., Drobny, H., and Freissmuth, W.

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20

Myocardial metabolism during pacing-induced ischemia in man. Temporal relationship with changes in post-stenotic coronary flow

Remme, W. J., Kruyssen, H. A. C. M., Krauss, X. H., Storm, C. J., and van Hoogenhuyze, D. C. A.

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21

Continuous recording of coronary venous potassium and pH during myocardial ischemia

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22

Continuous monitoring of coronary venous lactate in transient ischemia

Tommasini, G., and Tamagni, F.

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23

Myocardial temperature mapping after cold cardioplegia

Leguerrier, A., Rioux, C., Rosat, P., Marcade, E., Le Couls, H., Boulvard, J., Mottez, C., and Logeais, Y.

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24

Reduction of myocardial blood volume during regional ischemia

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