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29.04.10 08:17 Age: 129 days
Getting to the heart of the matter
The origin and early development of coronary vessels is unclear, although the textbook view is that they arise from the proepicardium — a transitory structure in the embryo that contacts and spreads over the developing heart to form its epithelial covering (epicardium). Red-Horse et al. now show that coronary vessels, including coronary arteries, actually derive from differentiated endothelial cells that sprout off the sinus venosus — the vein that returns blood to the embryonic heart.
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