29.04.10 08:23 Age: 8 yrs

Embryonic recall: myocardial regeneration beyond stem cell transplantation

The concept of stem cell transplantation in recovery of the heart never really scrutinized the developmental environment necessary to induce substantial changes. It is now time to shift gear to lessons learned in organogenesis and embryonic development and to study the regenerative forces established during evolution that are evidently lost in mammals. The hypothesis of "regional embryonic recall" is a starting point for the scientific community to improve our knowledge on the principles of myocardial regeneration potentially usable in the clinical arena. We have started a forum of interdisciplinary discussions ranging from the theoretical background to the establishment of clinically feasible methods to recover the heart beyond stem cell research.

Please read the full article by downloading this PDF-file: embryonic_recall.pdf