21.01.11 16:00 Age: 7 yrs

Remarkable review on dedifferentiation, transdifferentiation and reprogramming

embryonic_recall.pdf)

Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration
Chris Jopling, Stephanie Boue & Juan Carlos Izpisua Belmontep79 | doi:10.1038/nrm3043
http://www.nature.com/nrm/journal/v12/n2/full/nrm3043.html

Dedifferentiation, transdifferentiation and reprogramming could all be exploited to replace lost cells and tissues. Studies are aiming to understand the molecular details of these processes and to elucidate the advantages of one process over another for use in regenerative medicine.

A second interesting article was published recently on the periprocedural injury in elective PCI procedures, risk stratification for these patient as well as potential therapeutic options to prevent injury or its consequences. Although not mentioned in this article coronary sinus interventions might be a valuable tool in the prevention and will their application will be a focus in future reserach:

Review - Frontiers in cardiovascular medicine:
Girish Ganesha Babu, J. Malcolm Walker, Derek M. Yellon, and Derek J. Hausenloy
Peri-procedural myocardial injury during percutaneous coronary intervention: an important target for cardioprotection Eur Heart J (2011) 32(1): 23-31 doi:10.1093/eurheartj/ehq393